OptiSafe™
Eye Irritation Test
The gold standard in nonanimal ocular safety testing. OECD TG 496 validated, 100% sensitivity, and results in under 24 hours — with zero animal components of any kind.
Validated with international regulatory acceptance (OECD Test Guideline 496)
True nonanimal eye irritation test — no animal component of any kind
Rapid turnaround: quantitative results in less than 24 hours
100% sensitivity — no false negatives for non-irritant vs. rest discrimination
Patented tear chemistry reduces false positive rate to lowest of any nonanimal test
Plant-derived proteins, lipids, and nucleotides — zero animal ingredients
About OptiSafe™
The OptiSafe™ Eye Irritation Test (OS EIT) uses a macromolecular test matrix composed of plant-derived proteins, lipids, and nucleotides — no animal ingredient or component of any kind. The method measures the extent of damage to the macromolecular matrix upon exposure to a test chemical, and the measured extent of macromolecular damage is used to predict the toxicity of the tested chemical to the eye.
OptiSafe™ is the only nonanimal eye irritation test with a patented tear chemistry formulation that reduces the false positive rate to the lowest of any validated nonanimal ocular test — making it the most reliable choice for regulatory submissions.
Developed with NIH/NIEHS SBIR funding (Award R44ES025501) and validated under OECD Test Guideline 496 with full international regulatory acceptance.
Transparent Pricing
Test kits also available through InChemico.co
Industries We Serve
OptiSafe™ is accepted for regulatory submissions globally and applicable across all industries requiring ocular safety classification.
Cosmetics & Personal Care
EU Cosmetics Regulation compliance for eye area products, rinse-off formulations, and leave-on products.
Household Chemicals
GHS/CLP ocular hazard classification for cleaning agents, detergents, and consumer products.
Industrial Chemicals
Workplace safety classification for chemicals requiring ocular hazard labeling.
Pharmaceuticals
Ophthalmic formulation safety screening and excipient ocular compatibility testing.
Agrochemicals
Pesticide and herbicide ocular hazard classification for regulatory submission.
Medical Devices
Ocular biocompatibility screening for devices and materials with potential eye contact.
OptiSafe™ was developed with funding from the National Institute of Environmental Health Sciences (NIEHS) SBIR program, Award R44ES025501. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.
Get Results in Under 24 Hours
Submit your sample for OptiSafe™ testing. OECD TG 496 compliant results with full regulatory report. Starting at $2,100 per sample for volume orders.
Questions? Call us at +1 (714) 345-4689
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