Patent Granted · US12559784B2PCT WO2024177860A1NIH/NIEHS SBIR R44ES036065No Animal Tissue

DermaSafe SCT™ Skin Corrosivity Test

The only cell-free, shelf-stable in chemico skin corrosivity test with patented macromolecular damage technology. GHS multicategory classification. 98% accuracy. No animal tissue.

DermaSafe SCT™ — GHS skin corrosion warning symbol and chemical safety testing

About the DermaSafe SCT™

DermaSafe SCT™ is a novel in chemico (cell-free) test for classifying dermal corrosives. The test incubates the test substance with specific epithelial macromolecules extracted from food-source bovine tissue, then measures macromolecular damage spectrophotometrically. Shelf-stable, rapid, high-throughput. US Patent granted (US12559784B2); PCT WO2024177860A1 in national phase (EP, AU). Published in Toxicology In Vitro (2024).

  • Cell-free, shelf-stable, room-temperature incubation — no cell culture required
  • GHS multicategory classification: Not Corrosive · Category 1B+1C · Category 1A
  • Packing group assignment supported (Groups II and III combined)
  • 98% global corrosive/non-corrosive accuracy — highest of any validated method
  • GHS multicategory accuracy on par with RhE and Membrane Barrier methods
  • Published: Lebrun, Nguyen, Ho. Toxicology In Vitro. 2024. PMID: 39341469
98%Accuracy
NoneAnimal Tissue
3GHS Classes
GrantedUS Patent

Pricing

Per-sample pricing. Volume discounts apply automatically. Contact us for multi-project or annual contract rates.

QuantityUnit Price
1 sample$1,800
2–3 samples$1,600
4+ samples$1,500

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Research reported in this publication was supported by the National Institute of Environmental Health Sciences of the National Institutes of Health under Award Number R44ES036065. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

The Science Behind DermaSafe SCT™

Expand any topic below for detail on mechanism, validation data, GHS classification, patent protection, regulatory context, and NIH funding.

Ready to run DermaSafe SCT™ on your formulation?

Cell-free, shelf-stable, GHS multicategory results. No animal tissue. Accepted methodology for REACH, TSCA, DOT, IATA, and IMDG transport classification.

Patent US12559784B2PCT WO2024177860A1NIH/NIEHS SBIR Funded98% Accuracy